Genoa - SSC Napoli

Vitinha enters the new Serie A campaign with momentum after his clinical display helped Genoa dismantle Ascoli Calcio 1898 FC 4-1 in the Coppa Italia on 16 August 2026. The forward is expected to spearhead the attack at Stadio Luigi Ferraris alongside Lorenzo Colombo, with Tommaso Baldanzi tasked with providing the creative spark from midfield. Genoa will look to harness the confidence from their recent cup success to overcome a difficult historical trend against their visitors on this opening matchday.

SSC Napoli arrive for this 22 August 2026 clash with a new-look attack featuring Rasmus Hoejlund and Alisson Santos, though they face a defensive challenge following the injury to Alessandro Buongiorno. While they have enjoyed success in recent meetings, including a 3-2 victory at this venue on 7 February 2026, the visitors must quickly find their rhythm under competitive pressure. With Scott McTominay anchoring the midfield, Napoli will aim to disrupt Genoa's flow and control the tempo in a demanding curtain-raiser.